index
1005
Osmolality controls, 931
Osmoreceptors, 725
Osmosis, 3
Osmotic diarrhea, 145
Osmotic pressure, 932
Osteitis fibrosa cystica,
8 8 6
Osteoarthritis, 179
Osteoblasts, 173, 179, 875
Osteocalcin, 23, 179, 883, 889
Osteochondrodysplasia, 323
Osteoclasts, 9, 179
Osteocytes, 875
Osteogenesis imperfecta, 585, 586,
587, 890
Osteomalacia, 695,
8 8 8
Osteopetrosis, 875, 890
Osteoporosis, 179, 875, 878,
8 8 8
Osteoporosis (marble bone disease), 9
Osteosarcomas, 64
Ototoxic deafness, 535
Ouabain, 212
Ovarian, familial breast cancer, 612
Ovaries, 790, 795
Overproduction of PRPP, 631
Overweight, 515
Oxalates, 676
Oxaloacetate, 254, 277
/l-N-oxalyl-L-a,y
6
-diaminopropionic
acid, 181
Oxidant, 73
18-oxidase (CYP11B2), 704
Oxidation, 72
a-Oxidation, 373
ß
-Oxidation
energetics of, 371
«-oxidation, 374
Oxidation of fatty acids, 469
ß
-Oxidation of fatty acids, 368
Oxidation of glutathione, 302
Oxidation of pyruvate to acetyl-CoA, 236
Oxidation-reduction (redox) reactions,
72
Oxidative deamination, 335
Oxidative phase, 300
Oxidative phosphorylation, 247, 251, 257
mechanisms of, 257
uncoupling agents of, 261
uncoupling by ionophores, 261
Oxidizing agent, 73
Oxidoreductases,
8 6
5-oxoprolinase, 335
Oxygen dissociation curves for myoglobin
and hemoglobin, 649
Oxygen transport, 646
Oxyntic gland, 198
Oxyntic gland mucosa, 198
Oxytocin, 47, 702, 725, 733
Oxytocin, ADH (vasopressin), 724
P
3
IP-NMR, 12
P(properdin), 828
P-450 monooxygenase, 273
P-450 oxygenases, 690
p-aminobenzoic acid (PABA), 615
P-type ATPase, 896, 897
P. falciparum, 669
P/O, 257
P/O ratios, 257
P/O values, 257
pl
6
, 612
p21 GTPase, 611
p21 protein, 64
p21ras-GTPase, 612
p53, 612
p53 binding protein, 611
p53 gene, 64
PABA (p-aminobenzoic acid), 93, 215
Paclitaxel (taxol), 483
Pactamycin, 585
Paget’s disease,
8 8 8
PAI-1, 845, 846
PAI-2, 847
PAI-3 (protein C inhibitor), 847
Pain insensitivity, 340
Palindromes, 530
Pamaquine, 302
Pancreas, 127, 197,612
Pancreas, lung, colorectal, 611
Pancreatic, 702
Pancreatic amylase, 122, 291
Pancreatic cancers, 335
Pancreatic cholera, 224
Pancreatic duct, 202
Pancreatic duct obstruction, 127
Pancreatic enzyme deficiency, 219
Pancreatic gland, 201
Pancreatic hormones, 490
Pancreatic insufficiency, 221
Pancreatic islet /3 cells, 229
Pancreatic juice, 202, 217
Pancreatic lipase, 216, 218
Pancreatic necrosis, 600
Pancreatic polypeptide, 489, 490, 496
Pancreatic RNase, 600
Pantoprazole, 205
Pantothenic acid, 236, 924
Pantothenic acid (pantoyl-/!-alanine),
924
Papain, 460
Papaver somniferum, 735
Parabiosis, 516
Parachloromercuribenzoate, 959
Parafollicular (C-) cells, 769
Parahormones, 699
Parallel /
8
-pleated sheets, 55
Paramyotonia, 478
Paraoxonase, 446
Paraquat, 272
Parasympathetic activity, 82
Parasympathetic nervous stimulation,
197
Parathyroid, 702
Parathyroid hormone (PTH), 876, 884
Parathyroid hormone-related protein
(PTHrP), 876, 887
.
Parathyroid, adrenal, pituitary, 612
Paraventricular nucleus (PVN), 729
Parenteral nutrition, 26
Parietal cells, 9, 198, 204
Park nucleotide, 324
Parkinson’s disease, 269, 609, 761
Paroxysmal nocturnal hemoglobinuria
(PNH), 319
Partial pressures of oxygen, 648
a-particles in glycogen storage, 283
,
6
-particles in glycogen storage, 283
Parturition, 794
PAS staining, 139, 164
Pasteur effect, 245
PCMB, 959
Peanut agglutinin, 194
Peanuts, 333
Pearson’s marrow/pancreas syndrome,
270
Pellagra, 924
Penicillamine, 590, 896
D-penicillamine, 26
Penicillin-binding proteins (PBPs), 327
Penicillinase, 95
Penicillins, 192, 240, 327
Pentose phosphate pathway, 298, 620
Pentose phosphate pathway in red blood
cells, 301
PEPCK
(Phosphoenolpyruvatecarboxylinase),
276
cytoplasmic, 276
cytosolic, 277, 280
mitochondrial, 280
Pepsin, 214
Pepsinogen, 198, 214, 579
Peptic ulcer disease, 207
Peptide
Aj
6
42, 62
bonds, 17, 52, 53
random coil, 56
/3-turns, 56
Peptide hormones, 701
Peptide mapping, 959
Peptide sequence deduction, 46
Peptide synthesis
solid-phase technique, 48
Peptide, protein, or glycoprotein, 700
Peptidergic neurons, 202
